Fig. 1
From: Comparative analysis of alignment algorithms for macular optical coherence tomography imaging
Multiple OCT B-scans from the same patient scan (far left) are combined to form a 3D cube. The surface map is defined as the distance from the top of the data cube to the top of the nerve fiber layer (white arrow). It is expected that well aligned B-scans will result in a smooth surface map. The measure of the smoothness is defined as the mean value of the difference map which is created by applying a discrete Laplace operator over the surface map