Prospective and dichotomous study of biomarkers with swept-source OCT and OCT-angiography in naive patients with diabetic macular edema

Table 3 Characteristics of continuous variables in the dichotomous analysis

Variable	Group-2: Resistant patients (mean ± SD)	Group-1: Responsive patients (mean ± SD)	P-value
CMT pre (µm)	357.31 ± 70.768	323.20 ± 59.827	0.108
CMT post (µm)	295.08 ± 70.071	239.33 ± 15.486	0.006*
CCT pre (µm)	222.54 ± 63.112	221.00 ± 77.157	0.955
IOP pre (µm)	12.46 ± 1.450	12.87 ± 1.187	0.294
AADP pre (µm²)	1,246,377.23 ± 1,285,953.068	779,632.00 ± 634,783.417	0.294
AADP post (µm²)	500,560.69 ± 330,168.298	242,215.20 ± 146,900.633	0.004*
AASP pre (µm²)	239,734.62 ± 92,549.811	231,596.27 ± 93,279.435	0.819
VD pre	19.9523 ± 10.360	16.127 ± 4.329	0.233
VD pos	18.796 ± 6.347	12.366 ± 3.152	0.002*
BCVA pre	0.678 ± 0.235	0.765 ± 0.242	0.254
BCVA pos	0.496 ± 0.260	0.308 ± 0.119	0.029*
Duration of DM (years)	14.54 ± 9.439	18.80 ± 10.213	0.294
Age (years)	68.00 ± 10.504	65.73 ± 10.299	0.57

^*p < 0.05
BCVA: best corrected visual acuity; CMT: central macular thickness; CCT: central choroidal thickness; IOP: intraocular pressure; VD: vessel density; AASP: avascular area of the superficial plexus; AADP: avascular area of the deep plexus; DM: diabetic mellitus. Pre: pre-treatment; Post: post-treatment

ISSN: 2056-9920