Fig. 3
From: A pilot study of intraoperative melphalan to prevent recurrent PVR: the IOMPVR study

Images from patient 1 at various follow-up evaluations. Preoperatively: A, An UWF color fundus image shows vitreous opacities, macula off and inferior RD with a star pattern PVR CP6. B, An UWF FAF image shows a RD. Day 7 postoperatively, A, An UWF color fundus image shows vitreous opacities and a reattached retina. Laser scars are seen in the periphery. B, An UWF FAF image shows a reattached retina. C, A vertical B-scan SD-OCT image shows a reattached macula with absence of the outer retina. Day 30 postoperatively, A, An UWF color fundus image shows complete retinal reattachment. Laser scars are seen in the periphery. There are no signs of PVR recurrence. B, An UWF FAF image shows a reattached retina. Hypo-autofluorescent dots are present because of laser scars in the periphery and around the retinotomy beneath the optic disc. C, An UWF FA image shows leakage in the inferior part of the posterior pole. D, A vertical B-scan SD-OCT image shows foveal thinning. Small paracentral intraretinal cysts are seen at the level of the inner nuclear layer. Day 90 postoperatively, A, An UWF color fundus image shows a re-detachment of the inferior retina due to a posterior retinal tear (green arrow). Laser scars are seen in the periphery. There are no signs of PVR recurrence. B, An UWF FAF image shows re-detachment of the inferior retina. The retinal tear is hyper-autofluorescent (green arrow). C, An UWF FA image shows less leakage in the inferior posterior pole. D, An oblique B-scan SD-OCT image shows stability of both the foveal thinning and the paracentral intraretinal cysts